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LY450139

Pharmacokinetics: -> penetrates blood brain barrier Mechanism of action: 1) interferes with formation of Abeta -> reduces A beta in plasma, but not CSF 2) inhibits APP secretase gamma-secretase) Notes: Manufacturer: Eli Lily

General

miscellaneous pharmacologic agent

References

  1. Reuters (07/2004)
  2. http://www.medscape.com/viewarticle/477715