long palate, lung & nasal epithelium carcinoma-associated protein 4; BPI fold-containing family B member 4; ligand-binding protein RY2G5 (BPIFB4, C20orf186, LPLUNC4)

Function: 1) recognition & binding of specific classes of odorants 2) carrier protein, transporting odorants across the mucus layer to access receptor sites (putative) 3) primary defense mechanism: (putative) recognition & removal from the mucosa of a) potentially harmful odorants b) pathogenic microorganisms 4) clearing excess odorant from mucus to enable new odorant stimuli to be received Structure: - belongs to the BPI/LBP/plunc superfamily, BPI/LBP family Compartment: secreted (putative), cytoplasm Alternative splicing: named isoforms=2 Expression: expressed in nasal tissue

Properties

SIZE: entity length = 614 aa MW = 65 kD COMPARTMENT: cytoplasm MOTIF: signal sequence {1-18} glycine-rich region {131-226} N-glycosylation site {N273}

Database Correlations

UniProt P59827 PFAM correlations Entrez Gene 149954 Kegg hsa:149954

References

UniProt :accession P59827