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lipoprotein insulin resistance score
Score of 0-100 with 100 being the most insulin resistant
Procedure:
- nuclear magnetic resonance-based procedure
- combines results of 6 lipoprotein particle numbers & sizes based on their differential strengths of association with insulin resistance
- large VLDL-particles:
- insulin sensitive: <0.9 nmol/L
- intermediate: 0.9 - 6.9 nmol/L
- insulin resistant: >6.9 nmol/L
- small LDL-particles:
- insulin sensitive: <117 nmol/L
- intermediate: 117 - 526 nmol/L
- borderline: 527 - 839 nmol/L
- insulin resistant: >839 nmol/L
- large HDL-particles:
- insulin sensitive: >7.3 umol/L
- intermediate: 7.3 - 3.1 umol/L
- insulin resistant: <3.1 umol/L
- VLDL size:
- insulin sensitive: <42.4 nm
- intermediate: 42.4 - 52.5 nm
- insulin resistant: >52.5 nm
- LDL size:
- insulin sensitive: >21.2 nm
- intermediate: 21.2 - 20.4 nm
- insulin resistant: <20.4 nm
- HDL size:
- insulin Sensitive: >9.6 nm
- intermediate: 9.6 - 8.9 nm
- insulin Resistant: <8.9 nm
Insulin Sensitive: <27
Intermediate: 27 - 63
Insulin Resistant: >63 [2]
Clinical significance:
- unknown
- data on beneficial impact on outcomes after early identification of insulin-resistance is lacking
- advantage over conventional testing for glycemic control, and dyslipidemias is unclear
Related
lipoprotein
General
laboratory analysis
score
References
- Liposcience
http://www.liposcience.com/diabetes/clinicians/
- Mayo Clinic: NMR Lipoprofile
http://www.mayomedicallaboratories.com/test-catalog/print.php?unit_code=91959