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lipohypertrophy
Etiology:
- insulin
Pathology:
- thought to be the result of repeated trauma & possibly anabolic side effects of insulin
Clinical manifestations:
- occurs at injection site of repeated insulin injections
- palpable, rubbery growth
- hyperpigmentation uncommon
Adverse effects:
- labile control of blood glucose levels due to variable insulin absorption
Management:
- prevention
- rotation of the site of insulin administration
- use of finer needles
General
hypertrophy
References
- Verma R
Images in Clinical Medicine.
Insulin-Mediated Lipohypertrophy
N Engl J Med 2017; 377:573. August 10, 2017
PMID: 28792866 Free full text
http://www.nejm.org/doi/full/10.1056/NEJMicm1701235?