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lipase maturation factor 2 (transmembrane protein 112B, transmembrane protein 153, LMF2, TMEM112B, TMEM153)
Function:
- role in the maturation of specific proteins in the endoplasmic reticulum
- may be required for maturation & transport of active lipoprotein lipase (LPL) through the secretory pathway
Structure: belongs to the lipase maturation factor family
Compartment: endoplasmic reticulum
Alternative splicing: named isoforms=3
General
glycoprotein
membrane protein
Properties
SIZE: entity length = 707 aa
MW = 80 kD
COMPARTMENT: endoplasmic reticulum
MOTIF: transmembrane domain {10-30}
transmembrane domain {78-98}
transmembrane domain {102-122}
transmembrane domain {123-143}
transmembrane domain {165-185}
transmembrane domain {227-247}
transmembrane domain {259-279}
transmembrane domain {310-330}
transmembrane domain {364-384}
transmembrane domain {399-419}
N-glycosylation site {N489}
transmembrane domain {637-657}
Database Correlations
UniProt Q9BU23
Pfam PF06762
References
UniProt :accession Q9BU23