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levorphanol (Levo-Dromoran)
Tradename: Levo-Dromoran. DEA-controlled substance: class 2.
Dosage: 2-4 mg PO/SC every 6 hours.
Tabs: 2 mg.
Pharmacokinetics:
1) onset of action 10-60 minutes (oral)
2) duration of action 6-8 hours
Laboratory:
1) specimen: serum
2) methods: GLC, GC-MS, RIA, EIA
Mechanism of action: opiate
Interactions
drug interactions
drug adverse effects (more general classes)
General
opiate
opioid receptor agonist (narcotic)
Properties
MISC-INFO: elimination route LIVER
1/2life 13 HOURS
toxic-range >100 NG/ML
protein-binding 50%
QUOTE
(PREGNANCY_CATEGORY :VALUE C) NIL
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995