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levo-acetylmethadol; levomethadyl (LAAM, Orlaam)
Tradenames: LAAM, Orlaam. DEA controlled substance. Class 2. Withdrawn by manufacturer (Roxane) in 2003
-> due to adverse cardiac events & safer treatment options
Indications:
- narcotic dependence:
1) start 20-40 mg 3 times/week or QOD
2) do NOT give daily
3) dispense ONLY in DEA, FDA & state-approved treatment program
Dosage: oral: 10 mg/mL.
General
opiate
Properties
MISC-INFO: elimination route LIVER
pregnancy-category C
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Prescriber's Letter 11(2):suppl 2004