Contents

Search

CD85 or leukocyte immunoglobulin-like receptor family protein

Function: - may play role in T cell activation in peripheral blood - diagnostic use in hairy cell leukemia & plasma cell neoplasms Expression: - plasma cells - high levels - mantle zone B cells, germinal centers - lower levels - tissue macrophages - very low levels in some - peripheral blood: present in CD19+ B cells, 10% CD3+ T cells, some NK cells - dendritic cells Pathology: hairy cell leukemia - high levels

Specific

CD85b, ILT8 or leukocyte immunoglobulin-like receptor B6 CD85l, ILT9 or leukocyte immunoglobulin-like receptor A6 leukocyte immunoglobulin-like receptor subfamily A member 1; leukocyte immunoglobulin-like receptor 6; LIR-6; CD85 antigen-like family member I; CD85i (LILRA1, LIR6) leukocyte immunoglobulin-like receptor subfamily A member 2; leukocyte immunoglobulin-like receptor 7; LIR-7; immunoglobulin-like transcript 1; ILT-1; CD85 antigen-like family member H; CD85h (LILRA2, ILT1, LIR7) leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor 4; LIR-4; immunoglobulin-like transcript 6; ILT-6; monocyte inhibitory receptor HM43/HM31; CD85 antigen-like family member E; CD85e (LILRA3, ILT6, LIR4) leukocyte immunoglobulin-like receptor subfamily A member 4; immunoglobulin-like transcript 7; ILT-7; CD85 antigen-like family member G; CD85g (LILRA4, ILT7) leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte immunoglobulin-like receptor 9; LIR-9; immunoglobulin-like transcript 11; ILT-11; CD85 antigen-like family member F; CD85f (LILRA5, ILT11, LILRB7, LIR9) Leukocyte immunoglobulin-like receptor subfamily A member 6 (immunoglobulin-like transcript 8, ILT-8, leukocyte Ig-like receptor, LILRA6, ILT8) leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor 1; LIR-1; immunoglobulin-like transcript 2; ILT-2; monocyte/macrophage immunoglobulin-like receptor 7; MIR-7; CD85 antigen-like family member J; CD85j (LILRB1, ILT2, LIR1, MIR7) leukocyte immunoglobulin-like receptor subfamily B member 2; leukocyte immunoglobulin-like receptor 2; LIR-2; immunoglobulin-like transcript 4; ILT-4; monocyte/macrophage immunoglobulin-like receptor 10; MIR-10; CD85 antigen-like family member D; CD85d (LILRB2, ILT4, LIR2, MIR10) leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor 3; LIR-3; immunoglobulin-like transcript 5; ILT-5; monocyte inhibitory receptor HL9; CD85 antigen-like family member A; CD85a (LILRB3, ILT5, LIR3) leukocyte immunoglobulin-like receptor subfamily B member 4; leukocyte immunoglobulin-like receptor 5; LIR-5; immunoglobulin-like transcript 3; ILT-3; monocyte inhibitory receptor HM18; CD85 antigen-like family member K; CD85k (LILRB4, ILT3, LIR5) leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor 8; LIR-8; CD85 antigen-like family member C; CD85c (LILRB5, LIR8)

General

cluster-of-differentiation antigen; cluster designation antigen; CD antigen glycoprotein immunoglobulin superfamily protein

Properties

COMPARTMENT: plasma membrane MOTIF: glycosylation site membrane region

References

  1. Mason et al. Blood 99:3877-80, 2002.
  2. Protein Reviews on the Web http://mpr.nci.nih.gov/prow/guide/625330287_g.htm (10/10/02)
  3. http://www.pathologyoutlines.com/cdmarkers.html 20 May 2003