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leucine-rich repeat transmembrane protein FLRT3 (FLRT3, KIAA1469, UNQ856/PRO1865)

Function: - role in cell adhesion &/or receptor signaling Structure: - contains 1 fibronectin F3 module - contains 10 LRR repeats (leucine-rich repeats) Compartment: membrane Expression: - expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, heart

General

glycoprotein membrane protein

Properties

SIZE: MW = 73 kD entity length = 649 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-28} leucine-rich repeat SITE: 57-82 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 83-105 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 107-126 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 127-152 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 154-179 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 181-197 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 198-223 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 224-246 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N226} leucine-rich repeat SITE: 247-269 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 270-293 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N282} N-glycosylation site {N296} fibronectin type III domain or F3 module {406-501} transmembrane domain {529-549}

Database Correlations

OMIM 604808 UniProt Q9NZU0 PFAM correlations

References

UniProt :accession Q9NZU0