leucine-rich repeat transmembrane protein FLRT1 (fibronectin-like domain-containing leucine-rich transmembrane protein 1, FLRT1)

Function: - role in cell adhesion &/or receptor signaling Structure: - N-glycosylated - contains 1 fibronectin F3 moduel - contains 10 LRR repeats (leucine-rich repeats) Compartment: membrane Expression: expressed in kidney & brain

General

glycoprotein membrane protein

Properties

SIZE: MW = 71 kD entity length = 646 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-20} leucine-rich repeat SITE: 52-77 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 78-98 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 99-121 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 123-147 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 148-169 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 170-192 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 194-218 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 219-241 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N221} leucine-rich repeat SITE: 242-264 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 265-288 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N277} fibronectin type III domain or F3 module {406-501} transmembrane domain {525-545}

Database Correlations

OMIM 604806 UniProt Q9NZU1 PFAM correlations

References

UniProt :accession Q9NZU1