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leucine-rich repeat-containing protein 21; photoreceptor-associated LRR superfamily protein; retina-specific protein PAL (LRRC21, PAL, LRIT1)
Function:
- role in phototransduction (putative)
Structure:
- homodimer
- contains 1 fibronectin F3 domain
- contains 1 Ig-like C2-type domain (immunoglobulin-like)
- contains 6 LRR repeats (leucine-rich repeats)
Compartment: endoplasmic reticulum membrane
General
glycoprotein
leucine rich repeat & fibronectin type-3 domain-containing protein
membrane protein
Properties
SIZE: MW = 68 kD
entity length = 623 aa
COMPARTMENT: endoplasmic reticulum
MOTIF: signal sequence {1-21}
leucine-rich repeat
SITE: 58-81
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 82-105
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 106-129
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 131-153
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 154-177
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N156}
immunoglobulin superfamily domain {266-335}
MOTIF: cysteine residue {C275}
MODIFICATION: cysteine residue {C328}
N-glycosylation site {N296}
cysteine residue {C328}
MODIFICATION: cysteine residue {C275}
fibronectin type III domain or F3 module {427-519}
MOTIF: N-glycosylation site {N455}
Thr phosphorylation site {T486}
transmembrane domain {527-547}
leucine-rich repeat
SITE: 571-594
MOTIF: leucine residue (SEVERAL)
Database Correlations
UniProt Q9P2V4
PFAM correlations
References
UniProt :accession Q9P2V4