leucine-rich repeat & immunoglobulin-like domain-containing nogo receptor-interacting protein 3; leucine-rich repeat neuronal protein 6B; leucine-rich repeat neuronal protein 2 (LINGO3, LERN2, LRRN6B)

Structure: - contains 1 Ig-like C2-type domain (immunoglobulin-like) - contains 14 LRR repeats (leucine-rich repeats) Compartment: membrane;

General

glycoprotein leucine-rich repeat & immunoglobulin-like domain-containing nogo receptor-interacting protein (LINGO)

Properties

SIZE: entity length = 592 aa MW = 65 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-24} leucine-rich repeat SITE: 32-53 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 54-76 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 77-100 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 101-124 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 126-148 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N127} leucine-rich repeat SITE: 149-172 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 174-196 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N185} leucine-rich repeat SITE: 197-220 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 245-268 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N247} N-glycosylation site {N257} leucine-rich repeat SITE: 269-292 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N276} leucine-rich repeat SITE: 294-316 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 317-340 MOTIF: leucine residue (SEVERAL) N-glycosylation site {N324} leucine-rich repeat SITE: 342-364 MOTIF: leucine residue (SEVERAL) leucine-rich repeat SITE: 376-401 MOTIF: leucine residue (SEVERAL) immunoglobulin superfamily domain {407-496} MOTIF: cysteine residue {C429} MODIFICATION: cysteine residue {C480} cysteine residue {C480} MODIFICATION: cysteine residue {C429} N-glycosylation site {N488} N-glycosylation site {N512} transmembrane domain {532-552} alanine-rich region {576-579} MOTIF: alanine residue (SEVERAL)

References

UniProt :accession P0C6S8