Lethal(3)malignant brain tumor-like 2 protein; L(3)mbt-like 2 protein; H-l(3)mbt-like protein (L3MBTL2)

Function: - Polycomb group protein (PcG) - association with a chromatin remodeling complex - may contribute to prevent expression of genes that trigger entry of the cell into mitosis - component of the E2F6.com-1 complex Compartment: nucleus Alternative splicing: named isoforms=3 Structure: - contains 1 FCS-type zinc finger - contains 4 MBT repeats

General

nuclear protein zinc finger protein

Properties

SIZE: MW = 79 kD entity length = 705 aa COMPARTMENT: cell nucleus MOTIF: glutamate-rich region {17-20} MOTIF: glutamate residue (SEVERAL) Zinc finger NAME: Zinc finger SITE: 81-116 EFFECTOR-BOUND: Zn+2 MBT {179-283} MBT {291-391} MBT {397-500} MBT {508-604} lysine-rich region {620-624} MOTIF: lysine residue (SEVERAL)

Database Correlations

UniProt Q969R5 Pfam PF02820

References

UniProt :accession Q969R5