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lead nephropathy
Etiology:
1) pica
2) alcoholic beverages stored in lead crystal
3) lead batteries
4) aerosolized lead
Pathology:
1) accumulation of lead in proximal renal tubules
2) chronic tubulointerstitial nephritis
Clinical manifestations:
1) Fanconi's syndrome
2) renal insufficiency
3) hypertension
4) saturnine gout
Laboratory:
1) aminoaciduria
2) potassium excretory defects
3) glycosuria
4) serum lead concentrations are generally normal
5) excessive urine excretion of chelated lead after injection of EDTA (diagnostic)
Related
lead poisoning (plumbism)
lead [Pb]
Specific
saturnine gout
General
nephropathy
interstitial nephritis
References
Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998