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Laugier-Hunziker syndrome
Epidemiology:
- rare, > 100 cases described
- most cases in Europe France, Italy < U.S., U.K.
Genetics:
- sporadic
Clinical manifestations:
- similar mucocutaneous features to Peutz-Jeghers syndrome without systemic manifestations
- flat brown marks on the lips & inside the mouth
- brown stripes on the nails common
* images [1,2]
Differential diagnosis:
- Peutz-Jegher syndrome
Management:
- benign disorder, no treatment indicated
- Laser therapy for bothersome or difiguring lesions
General
mucosal disease
melanonychia; longitudinal melanonychia; melanonychia striata
syndrome
References
- DermNetNZ: Laugier-Hunziker syndrome
https://www.dermnetnz.org/topics/laugier-hunziker-syndrome/
- Mowad CM, Elston DM
Medscape: Laugier-Hunziker Syndrome
https://emedicine.medscape.com/article/1069034-overview
- Nayak RS, Kotrashetti VS, Hosmani JV.
Laugier-Hunziker syndrome.
J Oral Maxillofac Pathol. 2012 May;16(2):245-50.
PMID: 22923898 Free PMC Article