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kxgffkr

KXGFFKR or KXFFKR. X is either G, A, or V in KXFFKR, but may include I, L, C or M in KXGFFKR. KXGFFKR is found in cytoplasmic domains of all integrin alpha subunits. KXFFKR is found the in DNA-binding domain of the nuclear receptor superfamily. Calreticulin binds to this site.

Related

calreticulin; CRP55; calregulin; HACBP; ERp60; grp60 (CALR, CRTC)

General

binding site peptide motif

Properties

NAME: kxgffkr SITE: cytoplasmic domain FOR-BINDING-OF: calreticulin FORM: kxgffkr

References

  1. Burns K et al Modulation of gene expression by calreticulin binding to glucocorticoid receptor. Nature 367:476 1994 PMID: 8107808
  2. Dedhar et al Inhibition of nuclear hormone receptor activity by calreticulin. Nature 367:480 1994 PMID: 8107809