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Krueppel-like factor 9 (transcription factor BTEB1, basic transcription element-binding protein 1, BTE-binding protein 1, GC box-binding protein 1, KLF9, BTEB, BTEB1)
Function:
1) transcription factor that binds to GC box promoter elements
2) selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes
3) represses genes with a single GC box
Compartment: nucleus
General
Krueppel-like factor
Properties
SIZE: MW = 27 kD
entity length = 244 aa
COMPARTMENT: cell nucleus
MOTIF: acidic region {84-116}
MOTIF: acidic residue (SEVERAL)
Zn finger C2H2-type
SITE: 143-167
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 173-197
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 203-225
EFFECTOR-BOUND: Zn+2
Database Correlations
OMIM 602902
UniProt Q13886
Pfam PF00096
References
UniProt :accession Q13886