kinetochore protein Spc25 (hSpc25, SPC25, SPBC25, AD024)

Function: - component of kinetochore-associated NDC80 complex - required for kinetochore integrity & organization of stable microtubule binding sites in the outer plate of the kinetochore Compartment: - nucleus, kinetochore - localizes to kinetochores from late prophase to anaphase - localizes specifically to the outer plate of kinetochore

Properties

SIZE: MW = 26 kD entity length = 224 aa COMPARTMENT: cell nucleus MOTIF: SPBC24 interaction {1-144} MOTIF: KNTC2-NUF2 interaction {1-56} coiled coil {61-142} SPBC24 interaction {145-224}

Database Correlations

UniProt Q9HBM1 Pfam PF08234

References

UniProt :accession Q9HBM1