Killin (KLLN)

Function: - DNA-binding protein involved in S phase checkpoint control- coupled apoptosis by mediating p53/TP53-induced apoptosis - has the ability to inhibit DNA synthesis & induce S phase arrest coupled to apoptosis - has affinity to both double- & single-stranded DNA Compartment: nucleus Expression: by p53/TP53; direct transcription target of p53/TP53

Properties

SIZE: entity length = 178 aa MW = 20 kD COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 8-50

Database Correlations

OMIM 612105 UniProt B2CW77 Kegg hsa:1001

References

UniProt :accession B2CW77