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killer cell inhibitory receptor; killer cell immunoglobulin like receptor (KIR)

one of two distinct groups of NK cell receptors: KIRs (immunoglobulin superfamily proteins) & NKG2 receptors (C-type lectin superfamily proteins) Polymorphism: - the KIR genes are located in a segment of DNA on 19q13.4 in the leukocyte receptor complex that has undergone expansion & contraction over time, probably through unequal crossing-over; thus, KIR haplotypes vary in the number & types of genes, although a few framework loci, such as the gene KIR3DL1, are present on all or nearly all haplotypes

Related

killer cell lectin-like receptor C subfamily or NKG2 receptor

Specific

CD158 killer cell immunoglobulin like receptor 2D (KIR2D) killer cell immunoglobulin like receptor 3D (KIR3D) leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1, hLAIR1, CD305 antigen, LAIR1, CD305) leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2, CD306 antigen, LAIR2, CD306)

General

immunoglobulin superfamily protein

References

  1. UniProt :accession Q14943
  2. http://mpr.nci.nih.gov/prow/guide/679664748_g.htm