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killer cell immunoglobulin-like receptor-like protein KIR3DX1; leukocyte receptor cluster member 12 (KIR3DX1, KIR3DL0, LENG12)

Structure: - contains 2 Ig-like C2-type domains (immunoglobulin-like) Compartment: secreted (putative) Alternative splicing: named isoforms=2 Expression: expressed in NK-cells Note: - could be the product of a pseudogene - could constitute the ancestral killer immunoglobulin-like receptor gene in primates [2]

Related

killer cell inhibitory receptor; killer cell immunoglobulin like receptor (KIR)

General

glycoprotein secreted protein

Properties

SIZE: entity length = 352 aa MW = 39 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-16} immunoglobulin superfamily domain {17-112} MOTIF: cysteine residue {C49} MODIFICATION: cysteine residue {C94} N-glycosylation site {N78} cysteine residue {C94} MODIFICATION: cysteine residue {C49} immunoglobulin superfamily domain {224-311} MOTIF: cysteine residue {C244} MODIFICATION: cysteine residue {C295} cysteine residue {C295} MODIFICATION: cysteine residue {C244}

Database Correlations

UniProt Q9H7L2 Pfam PF00047 Kegg hsa:9001

References

  1. UniProt :accession Q9H7L2
  2. Sambrook JG, Bashirova A, Andersen H, Piatak M et al Identification of the ancestral killer immunoglobulin-like receptor gene in primates. BMC Genomics. 2006 Aug 15;7:209. PMID: 1691177