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ketosamine-3-kinase; fructosamine-3-kinase-related protein; FN3K-RP; FN3K-related protein (FN3KRP)
Function:
1) deglycating enzyme
2) phosphorylates the 3rd carbon of ketosamines (sugar moiety), psicosamines & ribulosamines, but not fructosamines, on third carbon of the sugar moiety
3) protein-bound psicosamine 3-phosphates & ribulosamine 3-phosphates areunstable & decompose under physiological conditions.
4) may play a role in freeing proteins from ribulosamines or psicosamines, thus phosphorylation leads to deglycation
Structure: belongs to the fructosamine kinase family
Expression: expressed in erythrocytes
General
kinase or ATP-phosphotransferase
Properties
SIZE: entity length = 309 aa
MW = 34 kD
MOTIF: Ser phosphorylation site {S20}
Database Correlations
OMIM 611683
UniProt Q9HA64
Pfam PF03881
Entrez Gene 79672
Kegg hsa:79672
References
UniProt :accession Q9HA64