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kelch-like protein 5 (KLHL5)
Structure:
- contains 1 BTB/POZ domain
- contains 6 kelch repeats
Compartment: cytoplasm, cytoskeleton
Alternative splicing:
- named isoforms=3
- at least one isoform may be due to intron retention
Expression:
- expressed in adrenal gland, ovary & thyroid gland
- lesser expression in lymph node, prostate, spinal cord, testis & trachea
General
kelch-like protein
Properties
SIZE: entity length = 755 aa
MW = 84 kD
COMPARTMENT: cytoplasm
MOTIF: BTB domain {220-287}
MOTIF: Zinc finger
NAME: Zinc finger
EFFECTOR-BOUND: Zn+2
kelch repeat {468-514}
kelch repeat {515-561}
kelch repeat {563-608}
kelch repeat {609-655}
kelch repeat {657-708}
kelch repeat {709-754}
Database Correlations
OMIM 608064
UniProt Q96PQ7
PFAM correlations
Entrez Gene 51088
References
UniProt :accession Q96PQ7