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kelch-like protein 2; actin-binding protein mayven (KLHL2)
Function:
- may play a role in organizing the actin cytoskeleton of neurons & glia
- binds actin
Structure:
- contains 1 BTB/POZ domain
- contains 6 kelch repeats
Compartment: cytoplasm, cytoskeleton
Expression:
- predominantly expressed in brain
General
kelch-like protein
Properties
SIZE: entity length = 593 aa
MW = 66 kD
COMPARTMENT: cytoplasm
MOTIF: BTB domain {56-123}
MOTIF: Zinc finger
NAME: Zinc finger
EFFECTOR-BOUND: Zn+2
kelch repeat {308-353}
kelch repeat {354-400}
kelch repeat {402-447}
kelch repeat {449-496}
kelch repeat {497-543}
kelch repeat {545-591}
Database Correlations
OMIM 605774
UniProt O95198
PFAM correlations
Entrez Gene 11275
Kegg hsa:11275
References
UniProt :accession O95198