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KDEL receptor (ER lumen protein-retaining receptor)
Function:
- retention of luminal endoplasmic reticulum proteins
- determines the specificity of the luminal ER protein retention system
- vesicular traffic through Golgi
- recognizes K-D-E-L (KDEL motif)
Compartment: endoplasmic reticulum membrane
Related
endoplasmic reticulum (ER)
Specific
KDEL receptor 1; ER lumen protein retaining receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; MAPK-activating protein PM23 (KDELR1, ERD21)
KDEL receptor 3; ER lumen protein retaining receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; (KDELR3)
KDEL receptor-2; ER lumen protein retaining receptor 2; KDEL endoplasmic reticulum protein retention receptor 2; ERD2-like protein 1; ELP-1 (KDELR2, ERD22)
General
receptor
transmembrane 7 protein
Properties
SIZE: entity length = 220 aa
COMPARTMENT: endoplasmic reticulum
MOTIF: transmembrane domain {TM1}
transmembrane domain {TM2}
transmembrane domain {TM3}
transmembrane domain {TM4}
transmembrane domain {TM5}
transmembrane domain {TM6}
transmembrane domain {TM7}
exoplasmic domain {N-TERMINAL}
ligand-binding site
cytoplasmic domain {C-TERMINAL}