K+ voltage-gated channel subfamily E member 1-like protein; AMME syndrome candidate gene 2 protein (KCNE1L, AMMECR2)

Structure: - belongs to the K⁺ channel KCNE family Compartment: - membrane; single-pass type 1 membrane protein Expression: - highly expressed in heart, skeletal muscle, brain, spinal cord & placenta Pathology: - defects in KCNE1L are involved in Alport syndrome with mental retardation midface hypoplasia & elliptocytosis

General

glycoprotein K+ channel subfamily E

Properties

SIZE: entity length = 142 aa MW = 15 kD COMPARTMENT: cellular membrane MOTIF: N-glycosylation site {N2} N-glycosylation site {N25} transmembrane domain {61-81} ION-PERMEABILITY: K+

Database Correlations

OMIM correlations UniProt Q9UJ90 Entrez Gene 23630 Kegg hsa:23630

References

UniProt :accession Q9UJ90