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jaw-winking syndrome; Marcus Gunn phenomenon; trigemino-oculomotor synkineses
Pathology:
- an exaggeration of a very weak physiologic co-contraction that has been disinhibited secondary to a congenital brainstem lesion
- stimulation of the trigeminal nerve by contraction of the pterygoid muscles of jaw results in the excitation of the branch of the oculomotor nerve that innervates the levator palpebrae superioris ipsilaterally (synkinesis)
Genetics:
- autosomal-dominant condition with incomplete penetrance
Clinical manifestations:
- nursing infants will have rhythmic upward jerking of their upper eyelid
Management:
- Treatment is usually unnecessary
General
syndrome
genetic disease of the nervous system
nervous system malformation
References
- Wikipedia: Marcus Gunn phenomenon
http://en.wikipedia.org/wiki/Marcus_Gunn_phenomenon
- Blaydon SM and Roy H
Medscape: Marcus Gunn Jaw-winking Syndrome.
http://emedicine.medscape.com/article/1213228-overview