isomerase

Enzyme catalyzing a change in the geometric or spatial configuration of a molecule.

Specific

3,2-trans enoyl CoA isomerase; dodecenoyl CoA delta-isomerase (DCI, ECI1) 3-beta hydroxy-5-ene steroid dehydrogenase type 1; steroid delta isomerase; progesterone reductase (HSD3B1, HSDB3A) 3-beta hydroxy-5-ene steroid dehydrogenase type 2; steroid delta isomerase; progesterone reductase (HSD3B2) 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase; cholestenol delta-isomerase; delta(8)-delta(7) sterol isomerase; D8-D7 sterol isomerase; emopamil-binding protein (EBP) 7-dehydrocholesterol delta-7 reductase AH receptor-interacting protein; AIP; aryl-hydrocarbon receptor-interacting protein; immunophilin homolog ARA9; HBV X-associated protein 2; XAP-2 (AIP, XAP2) alpha-methylacyl-CoA racemase (2-methylacyl-CoA racemase, AMACR) corticosterone side chain isomerase cytochrome p450 5A; thromboxane A [TxA] synthase 1 (TBXAS1, CYP5, CYP5A1) epimerase glucosamine-6-phosphate isomerase 1; glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; oscillin (GNPDA1, GNPI, HLN, KIAA0060) glucosamine-6-phosphate isomerase 2 (glucosamine-6-phosphate deaminase 2, GlcN6P deaminase 2, GNPDA 2, glucosamine-6- phosphate isomerase SB52, GNPDA2) hydroxypyruvate isomerase (endothelial cell apoptosis protein E-CE1, HYI) inositol-3-phosphate synthase (myo-inositol-1-phosphate synthase, MI-1-P synthase, MIP synthase, hIPS, myo-inositol 1-phosphate synthase A1, hINO1, INO1, ISYNA1) isopentenyl pyrophosphate isomerase mutase oxidosqualene-lanosterol cyclase (lanosterol synthase, LSS) peptidyl-prolyl cis/trans isomerase (PPIase) or rotamase peroxisomal 3,2-trans-enoyl-CoA isomerase; dodecenoyl-CoA isomerase; delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; DBI-related protein ;, DRS-1; hepatocellular carcinoma-associated antigen 88; NY-REN-1 antigen (PECI, DRS1, HCA88, ECI2) phenazine biosynthesis-like domain-containing protein (MAWD-binding protein, unknown protein 32 from 2D-page of liver tissue, PBLD, MAWBP) phosphoglucomutase or glucose phosphomutase phosphoglucomutase-2-like 1 (PMMLP, PGM2L1, BM32A) phosphohexose isomerase (PHI, phosphoglucose isomerase, PGI, phosphofructose isomerase, neuroleukin, NLK) phosphopentose isomerase proline racemase (L3HYPDH, C14orf149) prostacyclin synthase; prostaglandin I2 synthase (PTGIS, CYP8, CYP8A1) prostaglandin D synthase 1; prostaglandin-H2 D-isomerase; glutathione-independent PGD synthetase; beta-trace protein; lipocalin-type PGD synthase; L-PGDS (PTGDS) prostaglandin E synthase 2 (microsomal prostaglandin E synthase 2, mPGES-2, PTGES2, PGES2) protein disulfide isomerase (cellular thyroid hormone binding protein, prolyl 4-hydroxylase subunit beta, P4HB, ERBA2L, PDI, PDIA1, PO4DB) pseudouridylate synthase 7 homolog (PUS7, KIAA1897) pseudouridylate synthase 7 homolog-like protein (PUS7L) ribose-5-phosphate isomerase; phosphoriboisomerase (RPIA RPI) serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase (SRR) squalene oxidocyclase triosephosphate isomerase (TIM, triose-phosphate isomerase) (TPI1 TPI) tRNA pseudouridine synthase; tRNA-uridine isomerase; tRNA pseudouridylate synthase

Properties

MOTIF: active site

References

Principles of Biochemistry 6th ed., White, Handler, Smith, Hill, & Lehman (eds.) McGraw-Hill, NY 1978, pg 202