irradiation of cellular blood products

Indications: Prevention of graft versus host disease (GVHD) 1) well established risk - recipeints of allogeneic or autologous bone marrow transplant or stem cell transplants - patients receiving aggressive chemotherapy &/or radiation therapy - transfusions from blood relatives - HLA-matched platelet transfusions - congenital immunodeficiency syndromes - premature infants - intrauterine transfusions - neonatal exchange transfusions 2) risk less well established - recipients of solid organ transplants - nearly all cases of GVHD are caused by engraftment of lymphocytes from the donor organ rather than from blood products - HIV infection - transfusion associated GVHD has not been reported in patients with AIDS

Related

blood products blood transfusion electromagnetic radiation

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998