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intrinsic factor antibody (INTRINS) in serum

Indications: 1) gastritis 2) pernicious anemia (50%)* 3) hyperthyroidism (3-6%) 4) insulin-dependent diabetes mellitus (3-6%) * tesing for intrinsic factor Ab in the diagnosis of pernicious anemia not indicated [3] Specimen: - serum or plasma (EDTA) - avoid administration of vitamin B12 48 hours prior to drawing sample. - stable 4 hours at room temperature of 3 days refrigerated. - freeze at -20 degrees C for longer storage. Interferences: - false positives: - increased cyanocobalamin

Related

anti-intrinsic factor antibody (INTRINS) intrinsic factor; gastric intrinsic factor; IF; INF (GIF, IFMH) pernicious anemia; autoimmune gastritis

Specific

intrinsic factor blocking antibody in serum intrinsic factor IgG in serum

General

serology

References

  1. Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
  2. Intrinsic Factor Blocking Antibody Laboratory Test Directory ARUP: 70210
  3. Medical Knowledge Self Assessment Program (MKSAP) 16, American College of Physicians, Philadelphia 2012