proteolipid protein 2; intestinal membrane A4 protein; differentiation-dependent protein A4 (PLP2, A4)

Function: - may play a role in cell differentiation in the intestinal epithelium Structure: contains 1 MARVEL domain Compartment: membrane Expression: - enriched in colonic mucosa - expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt

General

glycoprotein membrane protein

Properties

SIZE: entity length = 152 aa MW = 17 kD COMPARTMENT: cellular membrane MOTIF: N-glycosylation site {N18} MARVEL {19-137} MOTIF: transmembrane domain {25-45} transmembrane domain {48-68} transmembrane domain {85-105} N-glycosylation site {N108} transmembrane domain {112-132}

Database Correlations

OMIM 300112 UniProt Q04941 Pfam PF01284 Entrez Gene 5355 Kegg hsa:5355

References

UniProt :accession Q04941