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interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28 (IL27A)
Function:
- subunit of interleukin-27 (IL27)
Structure:
- O-glycosylated (probable)
- belongs to the IL-6 superfamily
Compartment:
- secreted
- does not seem to be secreted without coexpression of EBI3
Expression:
- expressed in monocytes & in placenta
- transiently induced by LPS stimulation in monocytes
General
protein subunit
secreted protein
Properties
SIZE: entity length = 243 aa
MW = 27 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-28}
glutamate-rich region {164-176}
MOTIF: glutamate residue (SEVERAL)
Database Correlations
OMIM 608273
UniProt Q8NEV9
Entrez Gene 246778
Kegg hsa:246778
References
- UniProt :accession Q8NEV9
- Wikipedia; Note: interleukin-27 entry
http://en.wikipedia.org/wiki/interleukin_27
Component-of
interleukin-27 (IL-27)