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interleukin-19; melanoma differentiation associated protein-like protein; NG.1 (IL19, IL-19, ZMDA1)
Function:
1) inflammatory responses (putative)
2) up-regulates IL-6 & TNF-alpha
3) induces apoptosis (putative)
Structure: belongs to the IL-10 family
Compartment: secreted
General
glycoprotein
interleukin
Properties
SIZE: MW = 20 kD
entity length = 177 aa
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-24}
cysteine residue {C28}
MODIFICATION: cysteine residue {C121}
N-glycosylation site {N56}
cysteine residue {C75}
MODIFICATION: cysteine residue {C127}
cysteine residue {C76}
MODIFICATION: cysteine residue {C129}
cysteine residue {C121}
MODIFICATION: cysteine residue {C28}
cysteine residue {C127}
MODIFICATION: cysteine residue {C75}
cysteine residue {C129}
MODIFICATION: cysteine residue {C76}
N-glycosylation site {N135}
Database Correlations
OMIM 605687
UniProt Q9UHD0
Pfam PF00726
Entrez Gene 29949
Kegg hsa:29949
References
- Entrez Gene :accession 29949
- UniProt :accession Q9UHD0
- SeattleSNPs
http://pga.gs.washington.edu/data/il19/