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interferon-related developmental regulator 1; nerve growth factor-inducible protein PC4 (IFRD1)
Function:
- could play a role in regulating gene activity in the proliferative &/or differentiative pathways induced by NGF
- may be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (putative)
- interacts with PSIP1/LEDGF
Structure: belongs to the IFRD family
Expression: expressed in a variety of tissues
Related
interferon
General
phosphoprotein
secreted protein
Properties
SIZE: entity length = 451 aa
MW = 50 kD
COMPARTMENT: extracellular compartment
MOTIF: glycine-rich region {17-22}
MOTIF: Ser phosphorylation site {S21}
alanine-rich region {23-31}
MOTIF: alanine residue (SEVERAL)
alanine-rich region {144-149}
MOTIF: alanine residue (SEVERAL)
Database Correlations
OMIM 603502
UniProt O00458
PFAM correlations
Entrez Gene 3475
Kegg hsa:3475
References
UniProt :accession O00458