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integrin beta-like protein 1 (ten integrin EGF-like repeat domain-containing protein, osteoblast-specific cysteine-rich protein, ITGBL1, OSCP, TIED)

Structure: - contains ten tandem EGF-like repeats strikingly similar to those found in the cysteine rich 'stalk-like' structure of integrin beta-subunits Compartment: secreted (putative) Expression: - widely expressed in many tissues, but readily detectable only in aorta

General

glycoprotein secreted protein

Properties

SIZE: entity length = 494 aa MW = 54 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-23} Cysteine-rich tandem repeats {51-494} MOTIF: I {51-95} II {96-142} III {143-184} IV {185-230} V {231-275} VI {276-326} VII {327-367} VIII {368-414} N-glycosylation site {N405} IX {415-454} X {455-494}

Database Correlations

OMIM 604234 UniProt O95965 Pfam PF07974 Kegg hsa:9358

References

UniProt :accession O95965