integrin-beta 5 (ITGB5)

Function: - associates with integrin alpha-V (integrin alpha-V/beta-5) Structure: - belongs to the integrin beta chain family - contains 1 PSI domain - contains 1 VWFA domain Compartment: membrane

General

glycoprotein integrin-beta

Properties

SIZE: entity length = 799 aa MW = 88 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-23} PSI {27-76} MOTIF: cysteine residue {C28} MODIFICATION: cysteine residue {C463} cysteine residue {C36} MODIFICATION: cysteine residue {C46} cysteine residue {C39} MODIFICATION: cysteine residue {C75} cysteine residue {C46} MODIFICATION: cysteine residue {C36} cysteine residue {C49} MODIFICATION: cysteine residue {C64} cysteine residue {C64} MODIFICATION: cysteine residue {C49} cysteine residue {C75} MODIFICATION: cysteine residue {C39} VWFA domain {136-378} MOTIF: cysteine residue {C202} MODIFICATION: cysteine residue {C211} cysteine residue {C211} MODIFICATION: cysteine residue {C202} cysteine residue {C259} MODIFICATION: cysteine residue {C300} cysteine residue {C300} MODIFICATION: cysteine residue {C259} N-glycosylation site {N347} cysteine residue {C401} MODIFICATION: cysteine residue {C413} cysteine residue {C413} MODIFICATION: cysteine residue {C401} cysteine residue {C433} MODIFICATION: cysteine residue {C682} N-glycosylation site {N460} cysteine residue {C461} MODIFICATION: cysteine residue {C465} cysteine residue {C463} MODIFICATION: cysteine residue {C28} Cysteine-rich tandem repeats {465-630} MOTIF: consensus repeat {465-512} cysteine residue {C465} MODIFICATION: cysteine residue {C461} cysteine residue {C476} MODIFICATION: cysteine residue {C487} N-glycosylation site {N477} cysteine residue {C484} MODIFICATION: cysteine residue {C522} cysteine residue {C487} MODIFICATION: cysteine residue {C476} cysteine residue {C489} MODIFICATION: cysteine residue {C498} cysteine residue {C498} MODIFICATION: cysteine residue {C489} cysteine residue {C500} MODIFICATION: cysteine residue {C513} N-glycosylation site {N505} consensus repeat {513-554} cysteine residue {C513} MODIFICATION: cysteine residue {C500} cysteine residue {C522} MODIFICATION: cysteine residue {C484} cysteine residue {C528} MODIFICATION: cysteine residue {C533} cysteine residue {C530} MODIFICATION: cysteine residue {C563} cysteine residue {C533} MODIFICATION: cysteine residue {C528} cysteine residue {C535} MODIFICATION: cysteine residue {C548} cysteine residue {C548} MODIFICATION: cysteine residue {C535} cysteine residue {C550} MODIFICATION: cysteine residue {C555} N-glycosylation site {N552} consensus repeat {555-593} cysteine residue {C555} MODIFICATION: cysteine residue {C550} cysteine residue {C563} MODIFICATION: cysteine residue {C530} cysteine residue {C569} MODIFICATION: cysteine residue {C574} cysteine residue {C571} MODIFICATION: cysteine residue {C602} cysteine residue {C574} MODIFICATION: cysteine residue {C569} cysteine residue {C576} MODIFICATION: cysteine residue {C585} cysteine residue {C585} MODIFICATION: cysteine residue {C576} N-glycosylation site {N586} cysteine residue {C587} MODIFICATION: cysteine residue {C594} consensus repeat {594-630} cysteine residue {C594} MODIFICATION: cysteine residue {C587} cysteine residue {C602} MODIFICATION: cysteine residue {C571} cysteine residue {C608} MODIFICATION: cysteine residue {C613} cysteine residue {C610} MODIFICATION: cysteine residue {C657} cysteine residue {C613} MODIFICATION: cysteine residue {C608} cysteine residue {C615} MODIFICATION: cysteine residue {C625} cysteine residue {C625} MODIFICATION: cysteine residue {C615} cysteine residue {C628} MODIFICATION: cysteine residue {C631} cysteine residue {C631} MODIFICATION: cysteine residue {C628} cysteine residue {C635} MODIFICATION: cysteine residue {C644} cysteine residue {C641} MODIFICATION: cysteine residue {C714} cysteine residue {C644} MODIFICATION: cysteine residue {C635} N-glycosylation site {N654} cysteine residue {C657} MODIFICATION: cysteine residue {C610} cysteine residue {C661} MODIFICATION: cysteine residue {C690} cysteine residue {C682} MODIFICATION: cysteine residue {C433} cysteine residue {C690} MODIFICATION: cysteine residue {C661} N-glycosylation site {N705} cysteine residue {C714} MODIFICATION: cysteine residue {C641} transmembrane domain {720-742}

Database Correlations

OMIM 147561 UniProt P18084 PFAM correlations Entrez Gene 3693 Kegg hsa:3693