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integrator complex subunit 11 (Int11, INTS11, CPSF3L-like protein, protein related to CPSF subunits of 68 kD, RC-68, CPSF3L, RC68)

Function: 1) catalytic component of the Integrator complex 2) mediates the snRNAs 3' cleavage 3) HXHXDH motif essential for the endoribonuclease activity Compartment: nucleus, cytoplasm Alternative splicing: named isoforms=3

General

endoribonuclease enzyme catalytic subunit zinc finger protein

Properties

SIZE: MW = 68 kD entity length = 600 aa COMPARTMENT: cytoplasm cell nucleus MOTIF: HXHXDH {68-73}

Database Correlations

UniProt Q5TA45

References

UniProt :accession Q5TA45

Component-of

integrator complex (multiprotein complex integrator)