insulin receptor beta (INSRA)

Function: - contains tyrosine kinase activity of insulin receptor Structure: - membrane-spanning subunit - covalently linked to insulin receptor alpha Compartment: - plasma membrane

General

protein subunit tyrosine kinase (protein tyrosine kinase, PTK)

Properties

COMPARTMENT: cellular membrane STATE: active state MOTIF: glycosylation site cysteine residue {N-TERMINAL} MODIFICATION: cysteine residue {C-TERMINAL} transmembrane domain kinase domain MOTIF: ATP-binding site NAME: ATP-binding site binding site FOR-BINDING-OF: insulin receptor substrate 1 Tyr phosphorylation site