insulin gene enhancer protein ISL-2 (islet-2, ISL2)

Function: 1) transcriptional factor 2) defines subclasses of motor neurons that segregate into columns in the spinal cord 3) selection of distinct axon pathways Compartment: nucleus

General

phosphoprotein transcription factor (TF)

Properties

SIZE: MW = 40 kD entity length = 359 aa COMPARTMENT: cell nucleus MOTIF: LIM domain {25-86} MOTIF: cysteine residue (6) histidine residue Zn+2-binding site LIM domain {87-149} MOTIF: cysteine residue (6) histidine residue Zn+2-binding site Ser phosphorylation site {S157} homeodomain SITE: 191-250

Database Correlations

UniProt Q96A47 PFAM correlations

References

UniProt :accession Q96A47