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inflammatory markers (iAGE)
Clinical significance:
- inflammatory markers ESR & CRP are used in evaluation of inflammatory diseases
- procalcitonin is use to assess inflammation associated with infection
- inflammatory marker chemokine CXCL9 upregulates multiple genes implicated in inflammation & is involved in cellular senescence, vascular aging & adverse cardiac remodeling [2]
Related
acute phase protein
inflammation
General
endocrinology panel
References
- ARUP Consult: Inflammatory Markers
The Physician's Guide to Laboratory Test Selection & Interpretation.
https://arupconsult.com/content/inflammatory-markers
- Buck Institute for Research on Aging
'Clock' created to predict immunological health and chronic diseases of aging
Research highlights the critical role of the immune system in the aging process.
Science Daily. Science News. July 12, 2021
https://www.sciencedaily.com/releases/2021/07/210712122159.htm
- Sayed N, Huang Y, Nguyen K et al
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity,
immunosenescence, frailty and cardiovascular aging.
Nature Aging 2021
Not indexed in PubMed
https://www.nature.com/articles/s43587-021-00082-y
Components
C-reactive protein (CRP) in serum/plasma
C-X-C motif chemokine 9; gamma-interferon-induced monokine; monokine induced by interferon-gamma; HuMIG; MIG; small-inducible cytokine B9 (CXCL9, CMK, MIG, SCYB9)
erythrocyte sedimentation rate (ESR)
procalcitonin in serum (Vidas Brahms PCT Assay)