Search
import snRNP complex
Structure:
- consists of:
- KPNB1, SNUPN, SMN1 & ZNF259
General
molecular complex
Properties
SUBUNITS: snurportin-1
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: binding site
SITE: 1-159
FOR-BINDING-OF: exportin 1
MOTIF: KPNB1... interaction {1-65}
IBB {11-73}
binding site
SITE: 208-328
FOR-BINDING-OF: 2,2,7 trimethylated inverted GTP 5' cap structure
importin beta-1
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: acetylation site
SITE: 1-1
EFFECTOR-BOUND: acetyl
Importin N-terminal {21-101}
HEAT repeat {124-163}
HEAT repeat {168-207}
HEAT repeat {213-250}
HEAT repeat {317-357}
MOTIF: binding site
SITE: 329-342
FOR-BINDING-OF: IAB
Ran-GTP binding {334-419}
MOTIF: HEAT repeat {362-399}
HEAT repeat {404-441}
HEAT repeat {602-641}
HEAT repeat {687-726}
survival motor neuron protein-1
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: Ser phosphorylation site {S4}
Ser phosphorylation site {S5}
Ser phosphorylation site {S8}
P1 (binding site for SIP1) {13-44}
MOTIF: Thr phosphorylation site {T25}
Ser phosphorylation site {S28}
Ser phosphorylation site {S31}
Tudor domain
SITE: 91-151
proline-rich region
SITE: 195-203
MOTIF: proline residue (SEVERAL)
proline-rich region
SITE: 217-226
MOTIF: proline residue (SEVERAL)
P2 (binding site for SM B) {240-267}
MOTIF: proline-rich region
SITE: 244-248
MOTIF: proline residue (SEVERAL)
SYNCRIP interaction {279-294}
zinc finger protein 259
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: Zn finger C4-type
SITE: 51-83
EFFECTOR-BOUND: Zn+2
Zn finger C4-type
SITE: 259-291
EFFECTOR-BOUND: Zn+2
References
UniProt :accession O95149
Components
importin beta-1 subunit (karyopherin beta-1 subunit, KPNB1, nuclear factor P97, importin 90)
snurportin-1 (RNA U transporter 1, SNUPN, RNUT1, SPN1)
survival motor neuron protein-1; component of gems 1; Gemin-1 (SMN1, SMN, SMNT, SMN2, SMNC)
zinc finger protein 259; zinc finger protein ZPR1 (ZNF259, ZPR1)