Search
immunoglobulin superfamily member 10 (calvaria mechanical force protein 608, CMF608, IGSF10, CMF608)
Function:
- may be involved in the maintenance of osteochondroprogenitor cells pool (putative)
Structure:
- contains 12 Ig-like C2-type domain (immunoglobulin-like)
- contains 13 LRR repeats (leucine-rich repeats)
- contains 1 LRRNT domain
Compartment: secreted (putative)
Alternative splicing: named isoforms=3
General
glycoprotein
immunoglobulin superfamily protein
secreted protein
Properties
SIZE: MW = 291 kD
entity length = 2623 aa
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-28}
LRRNT {29-56}
leucine-rich repeat
SITE: 56-79
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 80-103
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 105-127
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 128-151
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 153-175
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 184-207
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 209-236
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N319}
leucine-rich repeat
SITE: 394-417
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N439}
immunoglobulin superfamily domain {461-567}
MOTIF: cysteine residue {C497}
MODIFICATION: cysteine residue {C551}
cysteine residue {C551}
MODIFICATION: cysteine residue {C497}
immunoglobulin superfamily domain {571-661}
MOTIF: cysteine residue {C595}
MODIFICATION: cysteine residue {C645}
N-glycosylation site {N627}
cysteine residue {C645}
MODIFICATION: cysteine residue {C595}
N-glycosylation site {N774}
N-glycosylation site {N999}
leucine-rich repeat
SITE: 1081-1104
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 1219-1244
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 1552-1577
MOTIF: leucine residue (SEVERAL)
immunoglobulin superfamily domain {1648-1739}
MOTIF: cysteine residue {C1670}
MODIFICATION: cysteine residue {C1723}
leucine-rich repeat
SITE: 1686-1710
MOTIF: leucine residue (SEVERAL)
cysteine residue {C1723}
MODIFICATION: cysteine residue {C1670}
immunoglobulin superfamily domain {1745-1836}
MOTIF: cysteine residue {C1767}
MODIFICATION: cysteine residue {C1820}
cysteine residue {C1820}
MODIFICATION: cysteine residue {C1767}
immunoglobulin superfamily domain {1841-1933}
MOTIF: cysteine residue {C1864}
MODIFICATION: cysteine residue {C1917}
leucine-rich repeat
SITE: 1881-1904
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N1899}
cysteine residue {C1917}
MODIFICATION: cysteine residue {C1864}
immunoglobulin superfamily domain {1941-2034}
MOTIF: N-glycosylation site {N1962}
cysteine residue {C1963}
MODIFICATION: cysteine residue {C2016}
cysteine residue {C2016}
MODIFICATION: cysteine residue {C1963}
immunoglobulin superfamily domain {2037-2135}
MOTIF: cysteine residue {C2060}
MODIFICATION: cysteine residue {C2119}
N-glycosylation site {N2101}
cysteine residue {C2119}
MODIFICATION: cysteine residue {C2060}
immunoglobulin superfamily domain {2141-2229}
MOTIF: cysteine residue {C2163}
MODIFICATION: cysteine residue {C2213}
cysteine residue {C2213}
MODIFICATION: cysteine residue {C2163}
immunoglobulin superfamily domain {2234-2331}
MOTIF: cysteine residue {C2261}
MODIFICATION: cysteine residue {C2313}
cysteine residue {C2313}
MODIFICATION: cysteine residue {C2261}
immunoglobulin superfamily domain {2337-2427}
MOTIF: cysteine residue {C2359}
MODIFICATION: cysteine residue {C2411}
cysteine residue {C2411}
MODIFICATION: cysteine residue {C2359}
immunoglobulin superfamily domain {2432-2518}
MOTIF: cysteine residue {C2454}
MODIFICATION: cysteine residue {C2506}
cysteine residue {C2506}
MODIFICATION: cysteine residue {C2454}
immunoglobulin superfamily domain {2528-2623}
MOTIF: cysteine residue {C2550}
MODIFICATION: cysteine residue {C2605}
cysteine residue {C2605}
MODIFICATION: cysteine residue {C2550}
Database Correlations
UniProt Q6WRI0
PFAM correlations
References
UniProt :accession Q6WRI0