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immunoglobulin superfamily domain

Ig constant chain domains & a single extracellular domain of MHC chains are related. These homologous domains are about 100 amino acid residues with a conserved intradomain disulfide. If intracellular, lacks disulfide bonds

Specific

Ig-like constant region-2-type domain Ig-like variable region-type domain immunoglobulin constant region; fragment crystallizable region (Fc) variable region

General

peptide motif exoplasmic domain

References

  1. Baron M, Norman DG, Campbell ID. Protein modules. Trends Biochem Sci. 1991 Jan;16(1):13-7. Review. PMID: 2053133
  2. prosite :accession PS00290