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high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Fc-epsilon RI-alpha; FcERI (FCER1A, FCE1A)
Function:
- alpha subunit of IgE receptor
Structure: contains 2 Ig-like (immunoglobulin-like) domains
Compartment: cell membrane
General
glycoprotein
plasma membrane protein
protein subunit
Properties
SIZE: entity length = 257 aa
MW = 30 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-25}
immunoglobulin superfamily domain {30-110}
MOTIF: N-glycosylation site {N46}
cysteine residue {C51}
MODIFICATION: cysteine residue {C93}
N-glycosylation site {N67}
N-glycosylation site {N75}
cysteine residue {C93}
MODIFICATION: cysteine residue {C51}
N-glycosylation site {N99}
immunoglobulin superfamily domain {111-193}
MOTIF: cysteine residue {C132}
MODIFICATION: cysteine residue {C176}
N-glycosylation site {N160}
N-glycosylation site {N165}
cysteine residue {C176}
MODIFICATION: cysteine residue {C132}
N-glycosylation site {N191}
transmembrane domain {206-224}
Database Correlations
OMIM 147140
UniProt P12319
Pfam PF00047
Kegg hsa:2205
References
UniProt :accession P12319