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iberiotoxin

Scorpion venom peptide. Inhibitor of Ca+2-activated &/or voltage-dependent K+ channels.

General

invertebrate-specific peptide toxin (hazardous material, poison)

Properties

MOTIF: cysteine residue {X} MODIFICATION: cysteine residue {X+22} cysteine residue {X+7} MODIFICATION: cysteine residue {X+29} cysteine residue {amyloid beta A4 protein-binding family A member 1 SIZE: entity length = 837 aa MW = 93 kD MOTIF: glutamate-rich region {67-70} MOTIF: glutamate residue (SEVERAL) Munc-18-1 binding {226-314} MOTIF: Ser phosphorylation site {S263} proline-rich region SITE: 294-328 MOTIF: proline residue (SEVERAL) proline-rich region SITE: 368-452 MOTIF: proline residue (SEVERAL) LIN-2/CASK binding {373-436} phosphotyrosine interaction domain NAME: phosphotyrosine interaction domain SITE: 457-643 PDZ domain NAME: PDZ domain SITE: 656-742 PDZ domain NAME: PDZ domain SITE: 747-822} MODIFICATION: cysteine residue {X+27} cysteine residue {X+22} MODIFICATION: cysteine residue {X} cysteine residue {X+27} MODIFICATION: cysteine residue {X+11} cysteine residue {X+29} MODIFICATION: cysteine residue {X+7}

References

Prosite :accession PS01138