hydroxysteroid 11-beta-dehydrogenase 1-like protein (short-chain dehydrogenase/reductase 10, 11-beta-hydroxysteroid dehydrogenase type 3, 11-beta-HSD3, HSD11B1L HSD3, SCDR10)

Structure: - belongs to the short-chain dehydrogenases/reductases (SDR) family Compartment: secreted (putative) Alternative splicing: named isoforms=8

General

11-OH steroid dehydrogenase; corticosteroid 11-beta dehydrogenase secreted protein

Properties

SIZE: entity length = 315 aa MW = 34 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-15} cofactor-binding site [29-62] COFACTOR-BOUND: NADP binding site SITE: 165-165 FOR-BINDING-OF: Substrate tyrosine residue {Y178} cofactor-binding site [182-182] COFACTOR-BOUND: NADP

Database Correlations

UniProt Q7Z5J1 Pfam PF00106 Kegg hsa:3748

References

UniProt :accession Q7Z5J1