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Humanin-like 11; HN11; MT-RNR2-like protein 11 (MTRNR2L11)
Function:
- biologically active peptide
- plays a role as a neuroprotective & antiapoptotic factor
Structure:
- belongs to the humanin family
Compartment:
- secreted
- cytoplasm
Genetics:
- product of a mitochondrial gene, MT-RNR2
- mechanisms allowing production & the secretion of humanin from the mitochondrial gene remaining unclear
- it is possible that the physiologically active humanin peptide is encoded by one of the related genes present in the nuclear genome [1,2]
General
Humanin-like protein
Properties
SIZE: entity length = 24 aa
MW = 3 kD
COMPARTMENT: mitochondria
cytoplasm
cell nucleus
Database Correlations
UniProt S4R3Y5
Pfam PF15040
References
- UniProt :accession S4R3Y5
- PMID: 19477263