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Howell-Jolly body
Etiology:
- they occur more frequently, & in greater numbers after splenectomy
- myelodysplastic syndrome
Structure:
- spherical or ovoid, eccentrically located granules, ~1 uM in diameter
Clinical significance:
- occasionally observed in stroma of circulating erythrocytes
- probably represent nuclear remnants
- significance is unknown
Related
Howell-Jolly bodies in blood
General
abnormal morphologic structure (malformation)