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housekeeping gene

Most mammalian genes contain either a TATA-box at 25-30 BP upstream of the transcriptional start site or a GC-rich element at -100 to -200 (as in housekeeping genes).

Specific

APP gene creatine kinase gene HMG CoA reductase gene insulin receptor gene LRP1 gene or apoE receptor gene or alpha-2 macroglbulin receptor gene prion gene surfeit [SURF] gene TGF-beta 1 gene transglutaminase-1 gene (TGM1) very low-density lipoprotein [VLDL] receptor gene

General

gene

Properties

MOTIF: CpG island {promoter region} transcription factor binding site transcriptional start site exon intron transcriptional termination site

References

  1. Salbaum et al EMBO J 7:2807 1988
  2. Manuelidis L. A view of interphase chromosomes. Science. 1990 Dec 14;250(4987):1533-40. Review. PMID: 2274784
  3. http://www.cgen.com/supp_info/Housekeeping_genes.html