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homeobox protein GBX-2; gastrulation & brain-specific homeobox protein 2 (GBX2)
Function:
- may act as a transcription factor for cell pluripotency & differentiation in the embryo
Structure: contains 1 homeobox DNA-binding domain
Compartment: nucleus (probable)
Expression:
- gastrulation & brain specific
General
DNA-binding protein
homeobox protein
Properties
SIZE: entity length = 348 aa
MW = 37 kD
COMPARTMENT: cell nucleus
MOTIF: proline-rich region
SITE: 56-63
MOTIF: proline residue (SEVERAL)
alanine-rich region {121-124}
MOTIF: alanine residue (SEVERAL)
homeodomain
SITE: 247-306
MOTIF: arginine-rich region {248-251}
MOTIF: arginine residue (SEVERAL)
Database Correlations
OMIM 601135
UniProt P52951
Pfam PF00046
Entrez Gene 2637
Kegg hsa:2637
References
UniProt :accession P52951